SGCA 抗原（重組蛋白）

Full name:

sarcoglycan alpha

Synonyms:

ADL; DAG2; 50DAG; DMDA2; LGMD2D; SCARMD1; adhalin

Swissprot:

Q16586

Gene Accession:

BC025702

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.