中文名稱: 兔抗ANKMY2多克隆抗體
英文名稱: Anti-ANKMY2 rabbit polyclonal antibody
別 名: ZMYND20
相關(guān)類別: 一抗
抗 原: ANKMY2
儲 存: 冷凍(-20℃)
宿 主: Rabbit
反應(yīng)種屬: Human, Mouse
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
Background: |
ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states. |
Applications: |
ELISA, IHC |
Name of antibody: |
ANKMY2 |
Immunogen: |
Fusion protein of human ANKMY2 |
Full name: |
ankyrin repeat and MYND domain containing 2 |
Synonyms: |
ZMYND20 |
SwissProt: |
Q8IV38 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human thyroid cancer and human cervical cancer |
IHC Recommend dilution: |
25-100 |