Background: |
This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). |
Applications: |
WB, IF |
Name of antibody: |
FGF23 |
Immunogen: |
Synthesized peptide derived from internal of human FGF23. |
Full name: |
fibroblast growth factor 23 |
Synonyms: |
ADHR; FGFN; HYPF; HPDR2; PHPTC |
SwissProt: |
Q9GZV9 |
WB Predicted band size: |
28 kDa |
WB Positive control: |
Jurkat cells lysate |
WB Recommended dilution: |
500-3000 |
IF positive control: |
Huvec cells |
IF Recommend dilution: |
100-500 |