兔抗FLNC多克隆抗體

Background:

This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

FLNC

Immunogen:

Synthetic peptide of human FLNC

Full name:

filamin C

Synonyms:

ABPA; ABPL; FLN2; MFM5; MPD4; RCM5; CMH26; ABP-280; ABP280A

SwissProt:

Q14315

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

30-150

WB Predicted band size:

291 kDa

WB Positive control:

LO2, NIH/3T3, A172 cell lysates

WB Recommended dilution:

500-2000