兔抗SELENOM多克隆抗體

Background:

The protein encoded by this gene belongs to the selenoprotein M/SEP15 family. The exact function of this protein is not known. It is localized in the perinuclear region, is highly expressed in the brain, and may be involved in neurodegenerative disorders. Transgenic mice with targeted deletion of this gene exhibit increased weight gain, suggesting a role for this gene in the regulation of body weight and energy metabolism. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal.

Applications:

ELISA, IHC

Name of antibody:

SELENOM

Immunogen:

Synthetic peptide of human SELENOM

Full name:

selenoprotein M

Synonyms:

SELM; SEPM

SwissProt:

Q8WWX9

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human cervical cancerHuman tonsil

IHC Recommend dilution:

25-100