購(gòu)物車
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021-54845833/15800441009
中文名稱： 兔抗NSD1多克隆抗體
英文名稱： Anti-NSD1 rabbit polyclonal antibody
別 名： STO; KMT3B; SOTOS; ARA267; SOTOS1
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： NSD1
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
NSD1 |
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Immunogen: |
Synthetic peptide of humanNSD1 |
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Full name: |
nuclear receptor binding SET domain protein 1 |
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Synonyms： |
STO; KMT3B; SOTOS; ARA267; SOTOS1 |
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SwissProt: |
Q96L73 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human prostate cancer |
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IHC Recommend dilution: |
20-100 |
