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021-54845833/15800441009
中文名稱： 兔抗NSMCE2多克隆抗體
英文名稱： Anti-NSMCE2 rabbit polyclonal antibody
別 名： NSE2; MMS21; ZMIZ7; C8orf36
抗 原： NSMCE2
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
反應(yīng)種屬： Human, Mouse, Rat
標 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
NSMCE2 is the E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. NSMCE2 acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
NSMCE2 |
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Immunogen: |
Full length fusion protein |
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Full name: |
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase |
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Synonyms： |
NSE2; MMS21; ZMIZ7; C8orf36 |
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SwissProt: |
Q96MF7 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human lung cancer and human brain |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
28 kDa |
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WB Positive control: |
293T cell |
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WB Recommended dilution: |
200-1000 |
