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  • 兔抗P4HB多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW21193
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:80
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中文名稱: 抗P4HB多克隆抗體


英文名稱: Anti-P4HB rabbit polyclonal antibody


別       名 P4HB; DSI; ERBA2L; GIT; P4Hbeta; PDI; PDIA1; PHDB; PO4DB; PO4HB; PROHB


相關(guān)類別: 一抗


儲(chǔ)      存: 冷凍(-20℃) 避光


宿      主: Rabbit


抗     原: P4HB


反應(yīng)種屬: Human, Mouse, Rat


標(biāo)  記  物: Unconjugate


克隆類型: rabbit polyclonal


技術(shù)規(guī)格

Background:

During their synthesis, secretory proteins translocate into the endoplasmic reticulum (ER) where they are post-translationally modified and properly folded. To reach their native conformation, many secretory proteins require the formation of intra- or inter-molecular disulfide bonds. This process is called oxidative protein folding. Protein disulfide isomerase (PDI) catalyzes the formation and isomerization of these disulfide bonds. Studies on mechanisms of oxidative folding suggest that molecular oxygen oxidizes the ER-protein Ero1, which in turn oxidizes PDI through disulfide exchange. This event is then followed by PDI-catalyzed disulfide bond formation in folding proteins.

Applications:

WB

Name of antibody:

P4HB

Immunogen:

Fusion protein of human P4HB

Full name:

prolyl 4-hydroxylase, beta polypeptide

Synonyms:

P4HB; DSI; ERBA2L; GIT; P4Hbeta; PDI; PDIA1; PHDB; PO4DB; PO4HB; PROHB

SwissProt:

P07237

WB Predicted band size:

57 kDa

WB Positive control:

THP1, SW620, 6T-CEM, NIH3T3 and RAW264.7 cells, liver and kidney tissue

WB Recommended dilution:

500-2000