兔抗FOXO1 多克隆抗體

Background:

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. Interacts with LRPPRC. Interacts with RUNX2; the interaction inhibits RUNX2 transcriptional activity and mediates the IGF1/insulin-dependent BGLAP expression in osteoblasts Interacts with PPP2R1A; the interaction regulates the dephosphorylation of FOXO1 at Thr-24 and Ser-256 leading to its nuclear import.

Applications:

ELISA, IHC

Name of antibody:

FOXO1

Immunogen:

Synthetic peptide of human FOXO1

Full name:

forkhead box O1

Synonyms：

FKH1, FKHR, FOXO1A

SwissProt:

Q12778

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer and Human liver cancer

IHC Recommend dilution:

25-100