兔抗GPM6A多克隆抗體

Background:

Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.

Applications:

ELISA, WB, IHC

Name of antibody:

GPM6A

Immunogen:

Fusion protein of human GPM6A

Full name:

glycoprotein M6A

Synonyms：

M6A; GPM6

SwissProt:

P51674

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human brain and human liver cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

31 kDa

WB Positive control:

Human fetal brain tissue

WB Recommended dilution:

1000-5000