中文名稱: 兔抗PSMC6多克隆抗體
英文名稱: Anti-PSMC6 rabbit polyclonal antibody
別 名: P44; p42; SUG2; CADP44; HEL-S-73
抗 原: PSMC6
儲 存: 冷凍(-20℃)
宿 主: Rabbit
反應種屬: Human, Mouse
相關類別: 一抗
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術規(guī)格
Background: |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12. |
Applications: |
ELISA, IHC |
Name of antibody: |
PSMC6 |
Immunogen: |
Fusion protein of human PSMC6 |
Full name: |
proteasome 26S subunit, ATPase 6 |
Synonyms: |
P44; p42; SUG2; CADP44; HEL-S-73 |
SwissProt: |
P62333 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human colorectal cancer; |
IHC Recommend dilution: |
20-100 |