兔抗APBA2多克隆抗體

Background:

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

APBA2

Immunogen:

Synthetic peptide of human APBA2

Full name:

amyloid beta (A4) precursor protein-binding, family A, member 2

Synonyms：

X11L; MINT2; LIN-10; HsT16821; X11-BETA; D15S1518E; MGC:14091

SwissProt:

Q99767

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and Human thyroid cancer

IHC Recommend dilution:

100-300