兔抗GPT2多克隆抗體

Background:

This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, WB

Name of antibody:

GPT2

Immunogen:

Synthetic peptide of human GPT2

Full name:

glutamic--pyruvic transaminase 2

Synonyms:

ALT2; GPT 2; MRT49

SwissProt:

Q8TD30

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

58 kDa

WB Positive control:

Human fetal brain tissue lysate

WB Recommended dilution:

200-1000