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  • 兔抗GRID2多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號 : TW22160
    • 應用 : 僅供科研使用
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中文名稱:兔抗GRID2多克隆抗體

英文名稱: Anti-GRID2 rabbit polyclonal antibody

別      名: GluD2

抗      原: GRID2

儲      存: 冷凍(-20℃) 避光

宿      主: Rabbit

反應種屬: Human Mouse Rat

相關類別: 一抗

標  記 物: Unconjugate

克隆類型: Unconjugate

技術規(guī)格

Background:

The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause cerebellar ataxia in humans.

Applications:

WB, IF

Name of antibody:

GRID2

Immunogen:

Synthesized peptide derived from internal of human GRID2.

Full name:

glutamate receptor, ionotropic, delta 2

Synonyms:

GluD2

SwissProt:

O43424

WB Predicted band size:

113 kDa

WB Positive control:

NIH/3T3 cells lysate

WB Recommended dilution:

500-3000

IF positive control:

Huvec cells

IF Recommend dilution:

100-500