Background: |
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein. |
Applications: |
WB |
Name of antibody: |
SP100 |
Immunogen: |
Synthesized peptide derived from Internal of human SP100. |
Full name: |
SP100 nuclear antigen |
Synonyms: |
lysp100b |
SwissProt: |
P23497 |
WB Predicted band size: |
100 kDa |
WB Positive control: |
HT29 cells lysate |
WB Recommended dilution: |
500-3000 |