兔抗SPTLC1多克隆抗體

Background:

This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.

Applications:

ELISA, WB, IHC

Name of antibody:

SPTLC1

Immunogen:

Fusion protein of human SPTLC1

Full name:

serine palmitoyltransferase, long chain base subunit 1

Synonyms：

HSN1; LBC1; LCB1; SPT1; SPTI; HSAN1

SwissProt:

O15269

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

53 kDa

WB Positive control:

Lovo cells

WB Recommended dilution:

200-1000