兔抗STXBP4多克隆抗體

Background:

Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.

Applications:

ELISA, IHC

Name of antibody:

STXBP4

Immunogen:

Fusion protein of human STXBP4

Full name:

syntaxin binding protein 4

Synonyms:

Synip

SwissProt:

Q6ZWJ1

IHC positive control:

Human breast cancer

IHC Recommend dilution:

25-100