Background: |
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. |
Applications: |
WB |
Name of antibody: |
TNNI3(Phospho-Ser43) |
Immunogen: |
Peptide sequence around phosphorylation site of Serine 43 (K-I-S(p)-A-S) derived from Human TNNI3. |
Full name: |
troponin I type 3 (cardiac) |
Synonyms: |
CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF |
SwissProt: |
P19429 |
WB Predicted band size: |
24 kDa |
WB Positive control: |
Jurkat cells lysates |
WB Recommended dilution: |
500-1000 |