兔抗VAMP2多克隆抗體

Background:

The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG.

Applications:

ELISA, WB, IHC

Name of antibody:

VAMP2

Immunogen:

Synthetic peptide of humanVAMP2

Full name:

vesicle-associated membrane protein 2 (synaptobrevin 2)

Synonyms：

SYB2; VAMP-2

SwissProt:

P63027

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and Human esophagus cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

13 kDa

WB Positive control:

A172, Jurkat and Hela cells, Mouse brain and Human fetal brain tissue

WB Recommended dilution:

500-2000