兔抗ARHGEF18多克隆抗體

Background:

Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified.

Applications:

ELISA, IHC

Name of antibody:

ARHGEF18

Immunogen:

Synthetic peptide of human ARHGEF18

Full name:

Rho/Rac guanine nucleotide exchange factor 18

Synonyms:

RP78; P114-RhoGEF

SwissProt:

Q6ZSZ5

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer and Human cervical cancer

IHC Recommend dilution:

25-100