兔抗ASCC2多克隆抗體

Background:

ASCC2 (activating signal cointegrator 1 complex subunit 2), also known as ASC1P100, is a 757 amino acid protein that is ubiquitously expressed and contains one CUE domain. The gene encoding ASCC2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

Applications:

ELISA, WB

Name of antibody:

ASCC2

Immunogen:

Synthetic peptide of human ASCC2

Full name:

activating signal cointegrator 1 complex subunit 2

Synonyms：

p100; ASC1p100

SwissProt:

Q9H1I8

ELISA Recommended dilution:

2000-5000

WB Predicted band size:

86 kDa

WB Positive control:

A431, 293T and hela cells

WB Recommended dilution:

500-2000