中文名稱:兔抗BCL2L10多克隆抗體
Background: |
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. |
Applications: |
ELISA, IHC |
Name of antibody: |
BCL2L10 |
Immunogen: |
Synthetic peptide of human BCL2L10 |
Full name: |
BCL2 like 10 |
Synonyms: |
Boo; Diva; BCL-B; bcl2-L-10 |
SwissProt: |
Q9HD36 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human brain |
IHC Recommend dilution: |
25-100 |