兔抗BGLAP多克隆抗體

Background:

Bone gamma-carboxyglutamic acid (Gla) protein, known as BGLAP, BGP or osteocalcin, is an abundant, non-collagenous protein component of bone that is produced by osteoblasts. In mice, osteocalcin is composed of a cluster of 3 genes known as OG1, OG2 and ORG, all of which can be found within a 23Kb span of genomic DNA. Human osteocalcin is a highly conserved, 46-50 amino acid, single chain protein that contains three vitamin K-dependent g-carboxyglutamic acid residues. Osteocalcin appears transiently in embryonic bone at the time of mineral deposition, where it binds to hydroxyapatite in a calcium-dependent manner.

Applications:

ELISA, IHC

Name of antibody:

BGLAP

Immunogen:

Synthetic peptide of human BGLAP

Full name:

bone gamma-carboxyglutamate (gla) protein

Synonyms：

OC; BGP; OCN

SwissProt:

P02818

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human thyroid cancer and Human brain

IHC Recommend dilution:

50-200