兔抗BMERB1多克隆抗體

Background:

C16orf45, also known as FLJ32618, is a 204 amino acid protein encoded by a gene mapping to human chromosome 16. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.

Applications:

ELISA, IHC

Name of antibody:

BMERB1

Immunogen:

Synthetic peptide of human BMERB1

Full name:

bMERB domain containing 1

Synonyms:

MINP; C16orf45

SwissProt:

Q96MC5

IHC positive control:

Human brain

IHC Recommend dilution:

10-50