兔抗BRAF(Ab-446)多克隆抗體

Background:

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance.

Applications:

WB, IHC

Name of antibody:

BRAF(Ab-446)

Immunogen:

Synthesized non-phosphopeptide derived from human B-RAF around the phosphorylation site of serine 446 (R-D-S(p)-S-D).

Full name:

B-Raf proto-oncogene, serine/threonine kinasep

Synonyms：

NS7; BRAF1; RAFB1; B-RAF1

SwissProt:

P15056

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

84 kDa

WB Positive control:

293 cells treated with insulin (0.01U/ml, 15mins) lysate

WB Recommended dilution:

500-3000