兔抗C5AR2多克隆抗體

Background:

This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

C5AR2

Immunogen:

Synthetic peptide of human C5AR2

Full name:

complement component 5a receptor 2

Synonyms:

C5L2; GPF77; GPR77

SwissProt:

Q9P296

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer and Human cervical cancer

IHC Recommend dilution:

30-150