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  • CD86 抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW4161
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱： CD86 抗原（重組蛋白）

英文名稱：CD86 Antigen (Recombinant Protein)

別    名： CD86 molecule; B70; B7-2; B7.2; LAB72; CD28LG2

儲(chǔ)    存： 冷凍（-20℃）

相關(guān)類別：抗原

概    述

Fusion protein corresponding to a region derived from 24-329 amino acids of human CD86

技術(shù)規(guī)格

Full name:

CD86 molecule

Synonyms:

B70; B7-2; B7.2; LAB72; CD28LG2

Swissprot:

P42081

Gene Accession:

BC040261

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.