兔抗CAST多克隆抗體

Background:

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Applications:

ELISA, WB, IHC

Name of antibody:

CAST

Immunogen:

Fusion protein of human CAST

Full name:

calpastatin

Synonyms：

BS-17

SwissProt:

P20810

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human cervical cancer and Human colon cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

77 kDa

WB Positive control:

Lovo cells

WB Recommended dilution:

500-2000