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中文名稱(chēng)： 兔抗WEE2多克隆抗體
英文名稱(chēng)： Anti-WEE2 rabbit polyclonal antibody
別 名： WEE1B
相關(guān)類(lèi)別：一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： WEE2
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1/CDC2 and acts as a key regulator of meiosis during both prophase I and metaphase II (PubMed:29606300). Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity). |
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Applications: |
ELISA, IHC |
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Name of antibody: |
WEE2 |
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Immunogen: |
Synthetic peptide of human WEE2 |
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Full name: |
WEE1 homolog 2 |
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Synonyms: |
OOMD5; WEE1B |
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SwissProt: |
P0C1S8 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer and Human colorectal cancer |
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IHC Recommend dilution: |
25-100 |
