兔抗CCL22多克隆抗體

Background:

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology.

Applications:

ELISA, IHC

Name of antibody:

CCL22

Immunogen:

Synthetic peptide of human CCL22

Full name:

C-C motif chemokine ligand 22

Synonyms:

MDC; ABCD-1; SCYA22; STCP-1; DC/B-CK; A-152E5.1

SwissProt:

O00626

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human ovarian cancer

IHC Recommend dilution:

25-50