兔抗CDC14B多克隆抗體

Background:

The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.

Applications:

ELISA, IHC

Name of antibody:

CDC14B

Immunogen:

Synthetic peptide of human CDC14B

Full name:

cell division cycle 14B

Synonyms:

CDC14B3; Cdc14B1; Cdc14B2; hCDC14B

SwissProt:

O60729

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer

IHC Recommend dilution:

25-100