兔抗CDK11A/CDK11B多克隆抗體

Background:

Cyclin-dependent kinases (CDKs) are a family of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells. They are present in all known eukaryotes, and their regulatory function in the cell cycle has been evolutionarily conserved. CDKs are relatively small proteins, with molecular weights ranging from 34 to 40 kDa, and contain little more than the kinase domain. By definition, a CDK binds a regulatory protein called a cyclin. Without cyclin, CDK has little kinase activity; only the cyclin-CDK complex is an active kinase. CDKs phosphorylate their substrates on serines and threonines, so they are serine-threonine kinases.

Applications:

ELISA, IHC

Name of antibody:

CDK11A/CDK11B

Immunogen:

Synthetic peptide of human CDK11A/CDK11B

Full name:

cyclin-dependent kinase 11A/B

Synonyms：

CDC2L2; CDC2L3; p58GTA; PITSLRE; CDK11-p46; CDK11-p58; CDK11-p110 / p58; PK58; CDK11; CLK-1; CDC2L1; p58CLK-1; CDK11-p46; CDK11-p58; p58CDC2L1; CDK11-p110

SwissProt:

B7ZVY7

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human thyroid cancer and Human brain

IHC Recommend dilution:

50-200