中文名稱: UBE4A 抗原(重組蛋白)
英文名稱: UBE4A Antigen (Recombinant Protein)
別 名: ubiquitination factor E4A; E4; UFD2; UBOX2
相關(guān)類別:抗原
儲(chǔ) 存: 冷凍(-20℃)
概 述
Full name: |
ubiquitination factor E4A |
Synonyms: |
E4; UFD2; UBOX2 |
Swissprot: |
Q14139 |
Gene Accession: |
BC112367 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |