小鼠抗ACTA2單克隆抗體

Background:

This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome.

Applications:

WB

Name of antibody:

ACTA2

Immunogen:

Fusion protein of human ACTA2

Full name:

actin alpha 2, smooth muscle

Synonyms:

ACTSA

SwissProt:

P62736

WB Predicted band size:

42 kDa

WB Positive control:

Human heart tissue, Rat heart tissue, Human left thymus tissue lysates

WB Recommended dilution:

1000-5000