小鼠抗ASL單克隆抗體

Background:

This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.

Applications:

WB, IHC

Name of antibody:

ASL

Immunogen:

Fusion protein of human ASL

Full name:

argininosuccinate lyase

Synonyms:

ASAL

SwissProt:

P04424

IHC positive control:

Human kidney tissue and Human liver tissue; Human endometrium tissue

IHC Recommend dilution:

200-500

WB Predicted band size:

52 KD

WB Positive control:

HepG2 cell lysate

WB Recommended dilution:

500-2000