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  • ZGPAT 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW6671
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:20
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中文名稱: ZGPAT 抗原(重組蛋白)

英文名稱: ZGPAT Antigen (Recombinant Protein)

別     名:
zinc finger CCCH-type and G-patch domain containing; ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847

儲(chǔ)     存 冷凍(-20℃)

相關(guān)類別:抗原

概     述

Fusion protein corresponding to a region derived from 332-531 amino acids of human ZGPAT

技術(shù)規(guī)格

Full name:

zinc finger CCCH-type and G-patch domain containing

Synonyms:

ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847

Swissprot:

Q8N5A5

Gene Accession:

BC019338

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.