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  • ZYX 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW6828
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:20
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中文名稱: ZYX 抗原(重組蛋白)

英文名稱: ZYX Antigen (Recombinant Protein)

別     名: zyxin; ESP-2; HED-2

相關(guān)類別:抗原

儲(chǔ)     存 冷凍(-20℃)

概     述

Fusion protein corresponding to a region derived from 373-572 amino acids of human ZYX

技術(shù)規(guī)格

Full name:

zyxin

Synonyms:

ESP-2; HED-2

Swissprot:

Q15942

Gene Accession:

BC008743

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.