小鼠抗ETS2單克隆抗體

Background:

ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM].

Applications:

WB, IHC, IF

Name of antibody:

ETS2

Immunogen:

Fusion protein of human ETS2

Full name:

v-ets avian erythroblastosis virus E26 oncogene homolog 2 (ETS2), transcript variant 1

Synonyms:

ETS2IT1

SwissProt:

P15036

IHC positive control:

human bladder tissue and carcinoma of human bladder tissue; human endometrium tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

53 kDa

WB Positive control:

HepG2 and Hela cell lysates

WB Recommended dilution:

200-1000