中文名稱 : 小鼠抗LZIC單克隆抗體
Background: |
LZIC (leucine zipper and CTNNBIP1 domain containing) is a 190 amino acid protein that belongs to the CTNNBIP1 family. Ubiquitously expressed, LZIC is found at highest levels in kidney and is upregulated in a few gastric carcinomas. The gene encoding LZIC maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. |
Applications: |
WB, IHC, IF |
Name of antibody: |
LZIC |
Immunogen: |
Fusion protein of human LZIC |
Full name: |
leucine zipper and CTNNBIP1 domain containing (LZIC) |
Synonyms: |
MGC15436 |
SwissProt: |
Q8WZA0 |
IHC positive control: |
adenocarcinoma of human breast tissue and carcinoma of human liver tissue; carcinoma of human prostate tissue and carcinoma of human bladder tissue |
IHC Recommend dilution: |
30-150 |
WB Predicted band size: |
21 kDa |
WB Positive control: |
HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates |
WB Recommended dilution: |
500-2000 |