兔抗HNRNPM多克隆抗體

Background:

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, WB, IHC

Name of antibody:

HNRNPM

Immunogen:

Synthetic peptide of human HNRNPM

Full name:

heterogeneous nuclear ribonucleoprotein M

Synonyms：

CEAR; HNRPM; HTGR1; NAGR1; HNRPM4; HNRNPM4; hnRNP M

SwissProt:

P52272

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human ovarian cancer and Human lung cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

78 kDa

WB Positive control:

293T, hela and A172 cell

WB Recommended dilution:

200-1000