兔抗IDH1多克隆抗體

Background:

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence.

Applications:

ELISA, WB, IHC

Name of antibody:

IDH1

Immunogen:

Fusion protein of human IDH1

Full name:

isocitrate dehydrogenase 1 (NADP+), soluble

Synonyms：

IDH; IDP; IDCD; IDPC; PICD

SwissProt:

O75874

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human cervical cancer and human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

47 kDa

WB Positive control:

Mouse intestinum tenue and liver tissue

WB Recommended dilution:

200-1000