兔抗IFI16多克隆抗體

Background:

This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

IFI16

Immunogen:

Synthetic peptide of human IFI16

Full name:

interferon, gamma-inducible protein 16

Synonyms:

PYHIN2; IFNGIP1

SwissProt:

Q16666

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer and human breast cancer

IHC Recommend dilution:

25-100