Background: |
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Applications: |
IHC |
Name of antibody: |
IRAK1(Phospho-Ser376) |
Immunogen: |
Peptide sequence around phosphorylation site of Serine 376(Q-S-S(p)-M-V) derived from Human IRAK1. |
Full name: |
interleukin-1 receptor-associated kinase 1 |
Synonyms: |
IRAK; pelle |
SwissProt: |
P51617 |
IHC positive control: |
Human brain tissue |
IHC Recommend dilution: |
50-100 |