Background:
This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants.
Applications:
ELISA, WB, IHC
Name of antibody:
KCNK9
Immunogen:
Synthetic peptide of human KCNK9
Full name:
potassium channel, subfamily K, member 9
Synonyms:
KT3.2; TASK3; K2p9.1; TASK-3
SwissProt:
Q9NPC2
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human liver cancer and Human colon cancer
IHC Recommend dilution:
100-300
WB Predicted band size:
42 kDa
WB Positive control:
Human paraneoplastic and normal kidney tissue
WB Recommended dilution:
500-2000
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