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  • 兔抗LATS1/2(Phospho-Thr1079/1041) 多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW11149
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱: 兔抗LATS1/2(Phospho-Thr1079/1041) 多克隆抗體

英文名稱: Anti-LATS1/2(Phospho-Thr1079/1041) rabbit polyclonal antibody

別     名: wts; WARTS/KPM

相關(guān)類別: 一抗

儲(chǔ)     存: 冷凍(-20℃) 避光

宿     主: Rabbit

抗     原: LATS1/2(Phospho-Thr1079/1041)

反應(yīng)種屬: Human Mouse

標(biāo) 記 物: Unconjugate

克隆類型: Unconjugate

技術(shù)規(guī)格

Background:

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A. In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding.

Applications:

IHC

Name of antibody:

LATS1/2(Phospho-Thr1079/1041)

Immunogen:

Peptide sequence around phosphorylation site of threonine 1079/1041 (E-F-T(p)-F-R) derived from Human LATS1/2 .

Full name:

large tumor suppressor kinase 1/2

Synonyms:

wts; WARTS/KPM

SwissProt:

O95835/Q9NRM7

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100