購(gòu)物車(chē)
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021-54845833/15800441009
中文名稱(chēng)： 兔抗ACO1多克隆抗體
英文名稱(chēng)： Anti-ACO1 rabbit polyclonal antibody
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： ACO1
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes. |
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Applications: |
ELISA, WB |
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Name of antibody: |
ACO1 |
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Immunogen: |
Synthetic peptide of human ACO1 |
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Full name: |
aconitase 1, soluble |
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Synonyms： |
IRP1; ACONS; IREB1; IREBP; IREBP1 |
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SwissProt: |
P21399 |
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ELISA Recommended dilution: |
2000-10000 |
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WB Predicted band size: |
98 kDa |
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WB Positive control: |
Mouse liver tissue |
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WB Recommended dilution: |
1000-5000 |
