中文名稱: 兔抗RHOB多克隆抗體
英文名稱: Anti-RHOB rabbit polyclonal antibody
別 名: ARH6, ARHB, RHOH6
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: RHOB
反應(yīng)種屬: Human, Mouse, Rat
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells. |
Applications: |
ELISA, WB |
Name of antibody: |
RHOB |
Immunogen: |
Synthetic peptide of human RHOB |
Full name: |
Ras homolog family member B |
Synonyms: |
ARH6, ARHB, RHOH6 |
SwissProt: |
P62745 |
ELISA Recommended dilution: |
2000-10000 |
WB Predicted band size: |
22 kDa |
WB Positive control: |
Mouse brain and fetal brain tissue |
WB Recommended dilution: |
1000-2000 |