Background: |
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.Required for maintaining the structural integrity of the Golgi apparatus, possibly by mediating interactions with cytoplasmic scaffolding proteins. |
Applications: |
WB, IHC, IF |
Name of antibody: |
RAB30 |
Immunogen: |
Fusion protein of human RAB30 |
Full name: |
RAB30, member RAS oncogene family (RAB30), transcript variant 2 |
Synonyms: |
RAB30, member RAS oncogene family |
SwissProt: |
Q15771 |
IHC positive control: |
human pancreas tissue and carcinoma of human thyroid tissue |
IHC Recommend dilution: |
30-150 |
WB Predicted band size: |
23 kDa |
WB Positive control: |
SVT2, Jurkat, MDCK, PC12, MCF-7 cell lysates |
WB Recommended dilution: |
200-1000 |