購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)：兔抗CISH多克隆抗體
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Background: |
The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
CISH |
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Immunogen: |
Fusion protein of human CISH |
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Full name: |
cytokine inducible SH2 containing protein |
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Synonyms: |
CIS; G18; SOCS; CIS-1; BACTS2 |
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SwissProt: |
Q9NSE2 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human esophagus cancer and Human thyroid cancer |
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IHC Recommend dilution: |
100-300 |
