技術(shù)規(guī)格
Background: |
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity). |
Applications: |
WB, IP |
Name of antibody: |
SWAP70 |
Immunogen: |
Fusion protein of human SWAP70 |
Full name: |
SWAP switching B-cell complex subunit 70 |
Synonyms: |
HSPC321; SWAP-70 |
SwissProt: |
Q9UH65 |
WB Predicted band size: |
69 kDa |
WB Positive control: |
COS7, 293T, C6, 3T3 and Hela cell lysates |
WB Recommended dilution: |
1000-5000 |